Methadone is contraindicated hinein patients with a known hypersensitivity to methadone hydrochloride or any other ingredient hinein methadone hydrochloride tablets.

Methadone should be given with caution and the initial dose reduced hinein certain patients, such as the elderly and debilitated and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy, or urethral stricture.

The endpoint of titration is achievement of adequate pain relief, balanced against tolerability of opioid side effects. If a patient develops intolerable opioid related side effects, the methadone dose, or dosing interval, may need to be adjusted.

Methadone should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Rein the selection of an initial dose of methadone hydrochloride tablets, attention should be given to the following:

The patient must, therefore, Beryllium monitored continuously for recurrence of respiratory depression and may need to be treated repeatedly with the narcotic antagonist. If the diagnosis is correct and respiratory depression is due only to overdosage of methadone, the use of other respiratory stimulants is not indicated.

Read the Patient Information that comes with methadone hydrochloride tablets before you take it and each time you get a new prescription.

Methadone is a mu-agonist opioid with an abuse liability similar to that of morphine and is a Schedule II controlled substance. Methadone, like morphine and other opioids used for analgesia, has the potential for being abused and is subject to criminal diversion.

There are restrictions on dispensing methadone for detoxification or maintenance programs. Not every pharmacy can dispense this medication for detoxification and maintenance. Talk to your doctor about where you can get this drug.

The severity of this syndrome will depend on the degree of physical dependence and the dose of the antagonist administered. If antagonists must be used to treat serious respiratory depression in the physically dependent patient, the antagonist should be administered with extreme care and by titration with smaller than usual doses of the antagonist.

Patients initiating treatment with methadone for opioid dependence should be reassured that the dose of methadone will “hold” for longer periods of time as treatment progresses.

Methadone treatment for analgesic therapy rein patients with acute or chronic pain should only be initiated if the potential analgesic or palliative care benefit of treatment with methadone is considered and outweighs the risks.

Do not take other medicines with methadone hydrochloride tablets without first talking with your doctor.

However, the risk is highest when Methadontabletten 10 mg online you first Keimzelle taking the drug and after a dosage increase. Your risk may also Beryllium higher if you’re older or already have breathing or lung problems.